What Is It?

Hydroxy B12 is a B12 supplement with the unique ability to help the body detoxify from low-level cyanide toxicity (such as from pesticide exposure or the use of certain medications). Hydroxy B12 helps rid the body of cyanide while delivering the essential benefits of vitamin B12.

How Does It Work?

Vitamin B12 (cobalamin) is one of the most complex vitamins in existence. Cyanocobalamin, the most common form of supplemental B12, must first be converted into hydroxocobalamin and then into adenosylcobalamin, the body’s B12 storage form and one of two active coenzyme forms. Adenosylcobalamin may also be converted into methylcobalamin, the other active coenzyme form of B12. Taking hydroxocobalamin allows the body to skip a step in this conversion process. Hydroxy B12 provides hydroxocobalamin in lozenge format for faster absorption. Hydroxocobalamin helps the body to eliminate cyanide, both by reacting with the toxin to form cyanocobalamin (which can then be excreted) and by enhancing the detoxification of cyanide through its conversion into the less toxic thiocyanate. Hydroxocobalamin has a long history of intravenous use for acute, life-threatening cyanide toxicity (such as during industrial disasters) and is approved for this use in many European countries.

Scientists have identified B12 deficiencies as risk factors for a multitude of conditions, including neuropathy, myelopathy, anemia, cardiovascular problems, and mood imbalances, among others.

AOR Advantage

Hydroxocobalamin is a unique form of vitamin B12, which is more readily converted into the active coenzyme form than cyanocobalamin, the most popular form used in supplements. Hydroxy B12 from AOR is one of the only B12 supplements available that provides this form of B12.